Atherosclerosis and cardial autonomic nervous system

Authors: Richard Imrich
Authors‘ workplace: Biomedicínske centrum SAV, Bratislava
Published in: AtheroRev 2018; 3(3): 175-178
Category: Reviews


The relationship between the autonomic nervous system and development of atherosclerosis is complex and includes several relatively independent mechanisms. First of all, increased sympathetic activation in the heart stimulates increased hemodynamic response, which may even lead to mechanical damage of the endothelium and arterial wall. Furthermore, the autonomic nervous system participates in vascular tone regulation and, along with other factors acting through the endothelium, it is involved in blood pressure regulation or development of hypertension, which indirectly contributes to the development of atherosclerosis. Given the important immunomodulatory characteristics of the autonomic nervous system, also the control of chronic inflammation is likely to play a significant role.

Key words:

autonomic dysfunction, hypertension, inflammation, stress

Received: 23. 8. 2018

Accepted: 27. 9. 2018

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Angiology Diabetology Internal medicine Cardiology General practitioner for adults
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