From dyslipidemia to ischemic heart disease and vice versa

Authors: Jan Piťha
Authors‘ workplace: Interní klinika 2. LF UK a FN v Motole, Praha ;  Laboratoř pro výzkum aterosklerózy Centra experimentální medicíny IKEM, Praha
Published in: AtheroRev 2016; 1(3): 120-124
Category: Reviews


To halt the progression and inducing regression of atherosclerosis it is necessary to reduce LDL-cholesterol to levels less than 1.3 mmol/l. This can be achieved with high doses of active statins, inhibitors of proprotein convertase subtili­sin/kexin 9, LDL/Lp(a) apheresis, or by combination of these methods. The latter two methods are the only substantially reducing other important lipid risk factor, lipoprotein(a). Triglycerides and HDL cholesterol can be improved mainly by lifestyle ganges.

Key words:
atherosclerosis – diagnosis-management – dyslipidemia – ischemic heart disease


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Angiology Diabetology Internal medicine Cardiology General practitioner for adults
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