Very low LDL cholesterol in acute coronary syndrome

Authors: Jan Piťha 1,2
Authors‘ workplace: Interní klinika 2. LF UK a FN Motol, Praha 1;  Centrum experimentální medicíny IKEM, Praha 2
Published in: AtheroRev 2020; 5(2): 93-97


Recommended very low target values of LDL cholesterol (less than 1.4, and 1.0 mmol/l in the case of recurrent events) are to be reached primary in patients with acute coronary syndrome (ACS), which are at the highest risk for subsequent events. Therefore, in these patients, dyslipidemia therapy should be initiated as soon and as aggressively as possible. In this context some uncertainties could be faced in patients with recent ACS and with very low LDL cholesterol levels (below 1.4 mmol/l). In the following article we focused on some practical aspects in the treatment of these patients, emphasizing that in most cases pharmacological treatment is absolutely needed even in this group. In principle, in patients at such risk there is no dangerously low LDL cholesterol level achieved by hypolipidemic treatment.


acute coronary syndrome – hypolipidemic therapy – low LDL cholesterol

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