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The 95th percentile of LDL-cholesterol in the Czech population: The Czech post- MONICA study


Authors: Renata Cífková 1,2;  Jan Bruthans 1;  Peter Wohlfahrt 1;  Alena Krajčoviechová 1;  Pavel Šulc 1;  Lenka Eremiášová 2;  Jan Pudil 2;  Aleš Linhart 2;  Jiří Widimský Jr 3;  Jan Filipovský 4;  Otto Mayer Jr 4;  Věra Lánská 5;  Rudolf Poledne 6;  Petr Stávek 6;  Vladimír Soška 7
Authors‘ workplace: Centrum kardiovaskulární prevence 1. LF UK a FTN, Praha 1;  II. interní klinika kardiologie a angiologie 1. LF UK a VFN v Praze 2;  III. interní klinika – endokrinologie a metabolismu 1. LF UK a VFN v Praze 3;  II. interní klinika LF UK a FN Plzeň 4;  Oddělení lékařské statistiky IKEM, Praha 5;  Centrum experimentální medicíny, Laboratoř pro výzkum aterosklerózy IKEM, Praha 6;  Oddělení klinické biochemie FN U sv. Anny v Brně 7
Published in: AtheroRev 2023; 8(1): 7-10
Category: Clinical Studies

Overview

According to the latest statistical data to date, cardiovascular disease (CVD) is the leading cause of death in the Czech Republic, accounting for 36.5% of deaths in men and 43.1% of deaths in women. According to data from the World Health Organization and the European Society of Cardiology, the Czech Republic is one of the countries with a high mortality rate from CVD. The main risk factors for CVD include dyslipidemia, LDL-cholesterol (LDL-C) has been identified as a major determinant of the risk for developing atherosclerosis. The aim of this analysis of the Czech post-MONICA study was to determine the 95th percentile values for LDL-C in a representative sample of the Czech population examined in 2015–2018. The 95th percentile values of LDL-C by age and sex are required to determine the probability of FH according to the Dutch Lipid Network Criteria.

Keywords:

cardiovascular disease – cardiovascular risk factors – Dutch Lipid Network Criteria – familiar hypercholesterolemia –population random sample


Sources

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Labels
Angiology Diabetology Internal medicine Cardiology General practitioner for adults
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