New alirocumab dosing regimen: 300 mg every 4 weeks
Authors:
Petr Ošťádal
Authors‘ workplace:
Komplexní kardiovaskulární centrum, Nemocnice Na Homolce, Praha
Published in:
AtheroRev 2021; 6(2): 103-107
Category:
Overview
The proprotein convertase subtilisin kexin type 9 inhibitor (PCSK9) alirocumab has been used in the lipid-lowering therapy as a 75mg or 150mg subcutaneous injection given every 2 weeks. Currently, alirocumab is available also as a single 300mg injection for administration every 4 weeks. This dosing regimen is supported by clinical studies that have evaluated its pharmacodynamic profile, efficacy, safety and also technical aspects of the newly developed autoinjector. Present article summarizes the available evidence for treatment with alirocoumab 300mg every 4 weeks.
Keywords:
alirocumab – dosing regimen – proprotein convertase subtilisin kexin type 9 (PCSK9)
Sources
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Angiology Diabetology Internal medicine Cardiology General practitioner for adultsArticle was published in
Athero Review
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