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Diabetes mellitus and heart failure: the role of SGLT2 inhibitors

Diabetes mellitus and heart failure: the role of SGLT2 inhibitors

SGLT2 inhibitors – gliflozins were introduced into clinical practice as peroral antidiabetics, acting by increased glucose excretion by urine using the blockade of SGLT2 co...

Authors: Jindřich Špinar, Jiří Vítovec, Lenka Špinarová
Issue: 1/2018

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Diabetes mellitus and resistance to therapy with ADP-receptor antagonists: Importance, possibilities of detection and therapeutic influence

Diabetes mellitus and resistance to therapy with ADP-receptor antagonists: Importance, possibilities of detection and therapeutic influence

Diabetes mellitus is connected with clopidogrel resistance, an independent risk factor of future ischemic events in patients undergoing percutaneous coronary interventions...

Authors: Matej Samoš, Tomáš Bolek, František Kovář, Peter Galajda, Marián Mokáň
Issue: 1/2018

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Fats in foods from health point of view

Fats in foods from health point of view

Fats play a significant role in terms of health. However, an average consumer does not understand a science behind them. There is a predominant tendency to avoid fats. The...

Issue: 1/2018

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Secondary and adverse effects of antihypertensive drugs

Secondary and adverse effects of antihypertensive drugs

It includes a brief overview of secondary and unwanted effects of basic antihypertensive drugs which may influence patients toward discontinuation of medication with the ensuing...

Authors: Jiří Vítovec, Jindřich Špinar
Issue: 1/2018

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Arterial hypertension – a risk factor for sudden vascular stroke

Arterial hypertension – a risk factor for sudden vascular stroke

Strokes are among the most common causes of morbidity and mortality, and in individuals who suffered stroke, subsequent long-term neurological deficit in a larger or smaller...

Authors: Ľudovít Gašpar, Andrea Komorníková, Veronika Vestenická
Issue: 1/2018

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Peripheral arterial disease of lower extremity and global cardiovascular risk

Peripheral arterial disease of lower extremity and global cardiovascular risk

Peripheral arterial disease (PAD) of lower extremity is predominantly a manifestation of atherothrombotic process. Effective cardiovascular risk treatment is underestimated in...

Authors: Denisa Čelovská, Viera Štvrtinová
Issue: 1/2018

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Perspectives on central systolic pressure in clinical practice

Perspectives on central systolic pressure in clinical practice

The basic characteristic of blood circulation in humans is given by the cyclical work of the heart, which ejects the blood pulse volume into the arteries. The workload of left...

Authors: Mária Potočárová, Jozef Bulas, Viera Kupčová, Marta Filková, Ján Murín
Issue: 1/2018

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Secondary dyslipidemia

Secondary dyslipidemia

Secondary dyslipidemia (DLP) arises as a result of other diseases or various exogenous influences. However, genetic predisposition, as it is known in the case of primary DLP...

Authors: Martin Šatný, Michal Vrablík
Issue: 3/2017

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Intensive treatment of dyslipidemia in regional outpatient cardiology office

Intensive treatment of dyslipidemia in regional outpatient cardiology office

We presented briefly initial experiences of outpatient cardiologist in the first ever MedPed center in the Orava region. Reduction of low-density lipoprotein cholesterol (LDL...

Issue: 3/2017

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The role of functional food and nutraceuticals in therapy of hypercholesterolemia

The role of functional food and nutraceuticals in therapy of hypercholesterolemia

Dyslipidemia, arterial hypertension, smoking and type 2 diabetes mellitus are the most important risk factors for cardiovascular diseases (CVD). The first step in treatment of...

Issue: 3/2017

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